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Oxaceprol

CAT: 0013-GTR19217274-02Size: 500 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19217274-02Size:500 mg
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Description
Oxaceprol is an established therapeutic agent for osteoarthritis. (In Vitro) :Oxaceprol, at 6 mg/kg/day for 7 days, significantly reduces both the surface area and wet weight of cotton pellet granulomas, being slightly less effective than indomethacin, 3 mg/kg.Oxaceprol (6–54 mg/kg/day) given therapeutically had no effect on the primary paw oedema response, but inhibits secondary lesions in the ears and tail.Oxaceprol does not inhibit the synthesis of prostaglandins in vitro, but markedly inhibits neutrophil infiltration into the joints of rats with adjuvant arthritis.
CAS Number
33996-33-7
Product Name Alternative
N-Acetyl-L-hydroxyproline
Field of Research
Pharmacology & Drug Discovery
Purity
>98% (HPLC)
Solubility
DMSO:1 mg/mL (577.47 mM)
Smiles
CC (=O) N1C[C@@H] (C[C@H]1C (=O) O) O
Molecular Formula
C7H11NO4
Molecular Weight
173.17
Storage Conditions
Storage temperature: -20°C. Stability: ≥ 2 years
Notes
For research use only.
Other Product Names
(2S4R) -1-acetyl-4-hydroxypyrrolidine-2-carboxylic acid

Chemical Information

Oxaceprol

Oxaceprol is an L-proline derivative that is L-proline substituted by acetyl and hydroxy groups at positions 1 and 4R, respectively. It is an anti-inflammatory drug used for the management of osteoarthritis. It has a role as an anti-inflammatory drug and a dermatologic drug. It is a member of acetamides, a pyrrolidinemonocarboxylic acid, a monohydroxypyrrolidine and a L-proline derivative.

CAS Number33996-33-7
PubChem CID65784
IUPAC Name(2S,4R)-1-acetyl-4-hydroxypyrrolidine-2-carboxylic acid
Molecular FormulaC7H11NO4
Molecular Weight173.17
XLogP-1.1
Topological Polar Surface Area77.8
Hydrogen Bond Donor Count2
Hydrogen Bond Acceptor Count4
Rotatable Bond Count1
Heavy Atom Count12
Formal Charge0
Complexity215
SMILES
CC(=O)N1C[C@@H](C[C@H]1C(=O)O)O
InChI
InChI=1S/C7H11NO4/c1-4(9)8-3-5(10)2-6(8)7(11)12/h5-6,10H,2-3H2,1H3,(H,11,12)/t5-,6+/m1/s1
InChIKey
BAPRUDZDYCKSOQ-RITPCOANSA-N
Chemical Structure
2D Structure
2D structure of Oxaceprol
CAS: 33996-33-7
CID: 65784
Formula: C7H11NO4
MW: 173.17
Interactive 3D Structure
Loading 3D structure...
View on PubChemRaw 3D data
Computed Properties
PropertyValue
Molecular Weight173.17
XLogP3-1.1
Hydrogen Bond Donor Count2
Hydrogen Bond Acceptor Count4
Rotatable Bond Count1
Exact Mass173.06880783
Monoisotopic Mass173.06880783
Topological Polar Surface Area77.8 Ų
Heavy Atom Count12
Formal Charge0
Complexity215
Isotope Atom Count0
Defined Atom Stereocenter Count2
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently-Bonded Unit Count1
Compound Is CanonicalizedYes

Alternative Products

CatalogName
MBS3842278-01Oxaceprol
HY-17490SOxaceprol-d3
A17342-25000Oxaceprol 25g
A17342-10000Oxaceprol 10g
HY-17490R-01Oxaceprol (Standard)
A17342-5000Oxaceprol 5g
A17342-10mM-DOxaceprol 10mM * 1mL in DMSO

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