C-82

CAT: 0013-GTR19216965-01Size: 100 mgDry Ice: NoHazardous: No

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CAT#:0013-GTR19216965-01Size:100 mg

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24/48H Stock Items & 2 to 6 Weeks non Stock Items.

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Description

C-82 is a specific CBP/β-catenin antagonist. It inhibits the binding between β-catenin and CBP and increases the binding between β-catenin and p300. (In Vitro) :C-82 inhibits the activation of isolated primary mouse quiescent hepatic stellate cells (HSCs) and promotes cell death in culture-activated HSCs. (In Vivo) :PRI-724 is phosphorylated-C-82 and is rapidly hydrolyzed to its active form C-82 in vivo, and pre-clinical studies have shown a very acceptable toxicity profile.

CAS Number

1422253-37-9

Purity

>98% (HPLC)

Smiles

[H][C@]12[C@H] (C) N (Cc3cccc4cccnc34) C (=O) [C@H] (Cc3ccc (O) cc3) N1C (=O) CN (C) N2C (=O) NCc1ccccc1

Molecular Formula

C33H34N6O4

Molecular Weight

578.673

Storage Conditions

Storage temperature: -20°C. Stability: ≥ 2 years

Notes

For research use only.

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C-82

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