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Pyriproxyfen

CAT: 0013-GTR19216833-01Size: 1 gDry Ice: NoHazardous: No
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CAT#:0013-GTR19216833-01Size:1 g
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Pyriproxyfen is an insecticide that acts as a biomimetic of juvenile hormone. (In Vivo) :Zebrafish male adults were acutely exposed to 0.001, 0.01 and 0.1 μg/mL pyriproxyfen for 16 h. Mitochondrial respiration of brain tissues was assessed. ROS generation was estimated using H2DCF-DA and MitoSOX. Calcium transport was monitored by Calcium Green 5 N. NO synthesis activity was estimated using DAF-FM-DA. Brain acetylcholinesterase showed an in vivo IC20 of 0.30 μmol/L pyriproxyfen, and an IC50 of 92.5 μmol/L. The inhibitory effect on zbAChE activity was competitive-like. Respiratory control of Complex I/II decreased significantly after insecticide exposure. The MitoSOX test showed that O2- generation had a pyriproxyfen dose-dependent effect. Brain tissue lost 50% of Ca2+ uptake capacity at 0.1 μg/mL pyriproxyfen. Ca2+ release showed a clear mitochondrial impairment at lower pyriproxyfen exposures.
CAS Number
95737-68-1
Product Name Alternative
S-31183
Purity
>98% (HPLC)
Solubility
In Vitro: DMSO : ≥ 100 mg/mL (311.17 mM)
Smiles
CC (COc1ccc (Oc2ccccc2) cc1) Oc1ccccn1
Molecular Formula
C20H19NO3
Molecular Weight
321.376
Storage Conditions
Storage temperature: -20°C. Stability: ≥ 2 years
Notes
For research use only.

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