Products for Research Use Only
RegisterLogin

1,2-Bis (2-iodoethoxy) ethane

CAT: 0013-GTR19216816-01Size: 1 gDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0013-GTR19216816-01Size:1 g
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Description
1,2-Bis (2-iodoethoxy) ethane is a PEG-based PROTAC linker. 1,2-Bis (2-iodoethoxy) ethane can be used in the synthesis of MT802 and SJF620. MT-802 and SJF620 are potent PROTAC BTK degraders with DC50s of 1 nM and 7.9 nM, respectively. (In Vitro) :1,2-Bis (2-iodoethoxy) ethane is a PROTAC linker, which refers to the PEG composition. 1,2-Bis (2-iodoethoxy) ethane can be used in the synthesis of a series of PROTACs, such as MT802 and SJF620. PROTAC MT802 has a ligand specific for BTK, and a ligand specific to a E3 ligase cereblon (CRBN) connected by polyethylene glycol (PEG) linker 1,2-Bis (2-iodoethoxy) ethane.
CAS Number
36839-55-1
Purity
>98% (HPLC)
Smiles
ICCOCCOCCI
Molecular Formula
C6H12I2O2
Molecular Weight
369.969
Storage Conditions
Storage temperature: -20°C. Stability: ≥ 2 years
Notes
For research use only.

Chemical Information

1,2-Bis(2-iodoethoxy)ethane
CAS Number36839-55-1
PubChem CID593436
IUPAC Name1,2-bis(2-iodoethoxy)ethane
Molecular FormulaC6H12I2O2
Molecular Weight369.97
XLogP2.2
Topological Polar Surface Area18.5
Hydrogen Bond Donor Count0
Hydrogen Bond Acceptor Count2
Rotatable Bond Count7
Heavy Atom Count10
Formal Charge0
Complexity53
SMILES
C(COCCI)OCCI
InChI
InChI=1S/C6H12I2O2/c7-1-3-9-5-6-10-4-2-8/h1-6H2
InChIKey
BCAGFJXMCZSAHD-UHFFFAOYSA-N
Chemical Structure
2D Structure
2D structure of 1,2-Bis(2-iodoethoxy)ethane
CAS: 36839-55-1
CID: 593436
Formula: C6H12I2O2
MW: 369.97
Interactive 3D Structure
Loading 3D structure...
View on PubChemRaw 3D data
Computed Properties
PropertyValue
Molecular Weight369.97
XLogP32.2
Hydrogen Bond Donor Count0
Hydrogen Bond Acceptor Count2
Rotatable Bond Count7
Exact Mass369.89267
Monoisotopic Mass369.89267
Topological Polar Surface Area18.5 Ų
Heavy Atom Count10
Formal Charge0
Complexity53.7
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently-Bonded Unit Count1
Compound Is CanonicalizedYes

Related Products

CatalogName
GTR19276643-011-Iodo-2- (2-iodoethoxy) ethane
GTR19275603-011-Chloro-2- (2-iodoethoxy) ethane
GTR19276107-012- (2-Iodoethoxy) ethan-1-ol
GTR19245824-01Bis[1,2-bis (diphenylphosphino) ethane]palladium (0)
GTR19275350-01N, N'- (Ethane-1,2-diyl) bis (2-bromoacetamide)
GTR19276715-01Ethyl 2- (2-iodoethoxy) acetate
GTR19275526-01((2-Iodoethoxy) methyl) benzene
GTR19276039-01Tert-Butyl 2- (2-iodoethoxy) acetate
GTR19275998-01Tert-Butyl (2- (2-iodoethoxy) ethyl) carbamate
GTR19226083-011,3-bis (carboxyethoxy) -2,2-bis (carboxyethoxy) propane

Alternative Products

CatalogName
BUP174351,2-Bis (2-iodoethoxy) ethane
MBS3615481-011,2-Bis(2-iodoethoxy)ethane
0420D 000051,2-Bis (2-Iodoethoxy) Ethane Stabilized 97% Extrapure
HY-W011264-011-Iodo-2- (2-iodoethoxy) ethane
HY-W1302261-Chloro-2- (2-iodoethoxy) ethane
C58967-1G1-iodo-​2-​{2-​[2-​ (2-​iodoethoxy) ​ethoxy]​ethoxy}​ethane
OR1025164-01(Ethane-1,2-Diylbis (Oxy) ) Bis (Ethane-2,1-Diyl) Bis (2-Ethylhexanoate)
B2100-251,2-Bis (2-nitrophenoxy) ethane
262655-011,2-Bis (2-aminophenoxy) ethane
MBS654095-011,2-Bis (2-aminophenoxy)ethane

Popular Products