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2'-Deoxy-2'-fluorocytidine

CAT: 0013-GTR19216499-01Size: 1 gDry Ice: NoHazardous: No
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CAT#:0013-GTR19216499-01Size:1 g
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Description
2'-Deoxy-2'-fluorocytidine is an nucleoside analog and inhibits of Crimean-Congo hemorrhagic fever virus (CCHFV) replication potently. (In Vitro) :2'-Deoxy-2'-fluorocytidine (EC50 = 61 ± 18 nM) has 200 x the potency of ribavirin (EC50 = 12.5 ± 2.6 μM), as well as 17 x the potency of T-705 (favipiravir), another compound with reported anti-CCHFV activity (EC50 = 1.03 ± 0.16 μM) . 2'-Deoxy-2'-fluorocytidine acts synergistically with T-705 to inhibit CCHFV replication without causing cytotoxicity.
CAS Number
10212-20-1
Purity
>98% (HPLC)
Solubility
In Vitro: H2O : 5 mg/mL (20.39 mM)
Smiles
Nc1ccn ([C@@H]2O[C@H] (CO) [C@@H] (O) [C@H]2F) c (=O) n1
Molecular Formula
C9H12FN3O4
Molecular Weight
245.21
Storage Conditions
Storage temperature: -20°C. Stability: ≥ 2 years
Notes
For research use only.

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