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Robinetin

CAT: 0013-GTR19216296-01Size: 100 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19216296-01Size:100 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Robinetin has antioxidant and antiradical activities, inhibits EYPC membrane lipid peroxidation and HbA glycosylation with high efficiency. (In Vitro) :Robinetin inhibits the DNA synthesis in Proteus vulgaris, and the RNA synthesis in S. aureus. Robinetin exhibits photo-induced excited-state intramolecular proton transfer resulting in ‘two color’ (in ‘blue-violet’ and ‘yellow-green’ regions) fluorescence characteristic of flavonols, the relative contributions between the two colors being strongly modulated by the local environment of the fluorophore. Robinetin (0.1-10 μM; 1 h) inhibits HIV integrase cleavage and integration in a dose-dependent manner. (In Vivo) :Pretreatment with 0.5, 12.5 or 25 mumol robinetin resulted in elevated induction of epidermal ODC by TPA at 6 h after TPA. However, treatment with 50 or 100 mumol robinetin diminished ODC induction at 6 h after TPA. Anti-mutagenicity was determined in the Salmonella typhimurium assay, Robinetin caused an 87% inhibition of mutagenicity by 2-aminoanthracene.
CAS Number
490-31-3
Product Name Alternative
3,3',4',5',7-Pentahydroxyflavone
Purity
>98% (HPLC)
Solubility
In Vitro: DMSO : 120 mg/mL (397.04 mM)
Smiles
Oc1ccc2c (c1) oc (-c1cc (O) c (O) c (O) c1) c (O) c2=O
Molecular Formula
C15H10O7
Molecular Weight
302.238
Storage Conditions
Storage temperature: -20°C. Stability: ≥ 2 years
Notes
For research use only.

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