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Cl-amidine TFA

CAT: 0013-GTR19216031-01Size: 100 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19216031-01Size:100 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Cl-amidine TFA is a cell-permeable, orally bioavailable pan-PAD inhibitor with IC50 values of 0.8 μM (PAD1), 6.2 μM (PAD3), and 5.9 μM (PAD4) . It is widely used in vitro to study PAD function in cancer models, where it induces apoptosis, and has demonstrated activity in preclinical in vivo studies for oncology and autoimmune disease research.
CAS Number
1043444-18-3
Field of Research
Cell Biology, Epigenetics & Chromatin, Immunology & Inflammation
Purity
98.11% (May vary between batches)
Smiles
C (C (O) =O) (F) (F) F.C (N[C@@H] (CCCNC (CCl) =N) C (N) =O) (=O) C1=CC=CC=C1
Molecular Formula
C16H20ClF3N4O4
Molecular Weight
424.8
Storage Conditions
-20°C
Notes
For research use only.

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