Products for Research Use Only
RegisterLogin

DBCO-NHS ester

CAT: 0013-GTR19213769-04Size: 25 mgDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0013-GTR19213769-04Size:25 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Description
DBCO-NHS ester is a cleavable linker featuring a 3-unit PEG spacer, designed for constructing antibody-drug conjugates (ADCs) . It enables precise bioconjugation for targeted drug delivery, facilitating both in vitro assay development and in vivo therapeutic research in oncology and beyond.
CAS Number
1353016-71-3
Product Name Alternative
DBCONHS ester, DBCO-NHS ester, DBCO NHS ester, Cleavable, ADCLinker, ADC linker, ADC Linker
Purity
98.02% (May vary between batches)
Solubility
10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (4.97 mM) ; DMSO:132.5 mg/mL (329.27 mM)
Smiles
O=C (CCC (=O) N1Cc2ccccc2C#Cc2ccccc12) ON1C (=O) CCC1=O
Molecular Formula
C23H18N2O5
Molecular Weight
402.4
Storage Conditions
-20°C
Notes
For research use only.

Chemical Information

DBCO-NHS Ester
CAS Number1353016-71-3
PubChem CID77078178
IUPAC Name(2,5-dioxopyrrolidin-1-yl) 4-(2-azatricyclo[10.4.0.04,9]hexadeca-1(16),4,6,8,12,14-hexaen-10-yn-2-yl)-4-oxobutanoate
Molecular FormulaC23H18N2O5
Molecular Weight402.4
XLogP1.7
Topological Polar Surface Area84
Hydrogen Bond Donor Count0
Hydrogen Bond Acceptor Count5
Rotatable Bond Count5
Heavy Atom Count30
Formal Charge0
Complexity778
SMILES
C1CC(=O)N(C1=O)OC(=O)CCC(=O)N2CC3=CC=CC=C3C#CC4=CC=CC=C42
InChI
InChI=1S/C23H18N2O5/c26-20(13-14-23(29)30-25-21(27)11-12-22(25)28)24-15-18-7-2-1-5-16(18)9-10-17-6-3-4-8-19(17)24/h1-8H,11-15H2
InChIKey
XCEBOJWFQSQZKR-UHFFFAOYSA-N
Chemical Structure
2D Structure
2D structure of DBCO-NHS Ester
CAS: 1353016-71-3
CID: 77078178
Formula: C23H18N2O5
MW: 402.4
Interactive 3D Structure
Loading 3D structure...
View on PubChemRaw 3D data
Computed Properties
PropertyValue
Molecular Weight402.4
XLogP31.7
Hydrogen Bond Donor Count0
Hydrogen Bond Acceptor Count5
Rotatable Bond Count5
Exact Mass402.12157168
Monoisotopic Mass402.12157168
Topological Polar Surface Area84 Ų
Heavy Atom Count30
Formal Charge0
Complexity778
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently-Bonded Unit Count1
Compound Is CanonicalizedYes

Related Products

CatalogName
GTR19261145-01DBCO-PEG13-NHS ester
GTR19233379-01DBCO-PEG2-NHS ester
GTR19225666DBCO-PEG8-NHS ester
GTR19237582-01DBCO-PEG24-NHS ester
GTR19231702-01DBCO-PEG5-NHS ester
GTR19175395-01DBCO-PEG4-NHS ester
GTR19267131-01DBCO-PEG6-NHS ester
GTR19225693DBCO-PEG1-NHS ester
GTR19225689-01DBCO-PEG12-NHS ester
GTR19225682-01DBCO-PEG3-NHS ester

Alternative Products

CatalogName
TRC-D194965-100MGDBCO-NHS Ester
4529-AATDBCO NHS Ester
FD176321Dbco- nhs ester
JFC87047-01DBCO-C6-NHS ester
572258DBCO-PEG4-NHS Ester
T89778-01DBCO-PEG24-NHS ester
T17783-01DBCO-PEG12-NHS ester
T17775-01DBCO-NHS ester 3
HY-140271-01DBCO-PEG1-NHS ester
sc-499348DBCO-PEG5-NHS ester

Popular Products