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2',3'-cGAMP sodium

CAT: 0013-GTR19213175-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19213175-01Size:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
2',3'-cGAMP sodium is a cyclic dinucleotide second messenger produced by cGAS upon cytosolic DNA sensing. It activates the STING pathway, leading to the induction of type I interferons and pro-inflammatory cytokines. This product is widely used in immunology research to study innate immune signaling in both cellular assays and animal models.
CAS Number
2734858-36-5
Product Name Alternative
Human Endogenous Metabolite, 2',3'-cGAMP sodium, 2'-3'-cyclic GMP-AMP sodium
Field of Research
Immunology & Inflammation, Metabolism Research
Purity
99.09% (May vary between batches)
Solubility
DMSO:0.9 mg/mL (1.25 mM) ; H2O:45 mg/mL (62.64 mM)
Smiles
OC1 ([H]) [C@] (OP (OC[C@] (O[C@@H] (N2C3=NC=NC (N) =C3N=C2) [C@@H]4O) ([H]) [C@@]4 ([H]) O5) (O[Na]) =O) ([H]) [C@H] (N6C (NC (N) =NC7=O) =C7N=C6) O[C@]1 ([H]) COP5 (O[Na]) =O
Molecular Formula
C20H22N10Na2O13P2
Molecular Weight
718.37
Storage Conditions
-20°C
Notes
For research use only.

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