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RAGE/SERT-IN-1

CAT: 0013-GTR19213079-01Size: 25 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19213079-01Size:25 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
RAGE/SERT-IN-1 is a dual-target inhibitor of the receptor for advanced glycation end products (RAGE) and the serotonin transporter (SERT), with IC50 values of 8.26 μM and 31.09 nM, respectively. This orally active compound has demonstrated neuroprotective effects against Aβ-induced toxicity in vitro and alleviates depressive-like behaviors in mouse models, supporting research into Alzheimer's disease and depression comorbidity.
CAS Number
2766739-35-7
Field of Research
Neuroscience
Smiles
CCCCC1=C (N=C (S1) C2CCN (CC2) CCCCC3=CN (C4=C3C=C (C=C4) C#N) C) C5=CC=C (C=C5) OC6=CC=C (C=C6) Cl
Molecular Formula
C38H41ClN4OS
Molecular Weight
637.28
Storage Conditions
-20°C
Notes
For research use only.

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