Products for Research Use Only

RET-IN-20

CAT: 0013-GTR19212225-01Size: 25 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19212225-01Size:25 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
RET-IN-20 is a potent small molecule RET inhibitor with an IC50 of 13.7 nM. It suppresses p-Ret and p-Shc signaling, leading to inhibited proliferation, induced apoptosis, and demonstrated anti-tumor activity in relevant research models for oncology studies.
Field of Research
Cell Biology, Signal Transduction
Smiles
CN1C=C (C (=N1) NC2=CC (=C (C=C2) OC3=C4C=C (C (=CC4=NC=C3) OC) C (=O) N) F) C (=O) NC56CC7CC (C5) CC (C7) C6
Molecular Formula
C32H33FN6O4
Molecular Weight
584.64
Storage Conditions
-20°C
Notes
For research use only.