Products for Research Use Only

AS-99

CAT: 0013-GTR19212028-01Size: 25 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19212028-01Size:25 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
AS-99 is a potent and selective first-in-class inhibitor of the ASH1L histone methyltransferase, demonstrating anti-leukemic activity. It inhibits proliferation and induces apoptosis in vitro, while effectively reducing leukemia burden in vivo by downregulating critical MLL fusion oncogene targets.
Field of Research
Cell Biology, Epigenetics & Chromatin
Smiles
CN1CC (C (NCC2=CC3=C (C (C4=CC (C (N) =S) =CC=C4) =CN3C5CCN (S (=O) (C (F) (F) F) =O) CC5) C=C2) =O) C1.Cl
Molecular Formula
C27H31ClF3N5O3S2
Molecular Weight
630.14
Storage Conditions
-20°C
Notes
For research use only.