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AF3442

CAT: 0013-GTR19212479-01Size: 25 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19212479-01Size:25 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
AF3442 is a potent and selective inhibitor of microsomal prostaglandin E synthase-1 (mPGES-1), demonstrating an IC50 of 0.06 μM in vitro. It effectively suppresses PGE2 production in human monocytes without redirecting PGH2 metabolism to other prostaglandin pathways, making it a valuable tool for investigating inflammation and pain in both cellular and animal models.
CAS Number
924636-93-1
Smiles
C (C) N1C=2C (C=3C1=CC=CC3) =CC (NC (=O) C4=C (C (F) (F) F) C=CC=C4) =CC2
Molecular Formula
C22H17F3N2O
Molecular Weight
382.38
Storage Conditions
-20°C
Notes
For research use only.

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