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Sulfo-SMCC sodium

CAT: 0013-GTR19216762-01Size: 500 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19216762-01Size:500 mg
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Description
Sulfo-SMCC sodium is a commonly used hetero-bifunctional, non-cleavable ADC crosslinker bearing N-hydroxysuccinimide (NHS) ester and maleimide groups to react with primary amines and sulfhydryl groups, respectively. (In Vitro) :The crosslinker Sulfo-SMCC consists of a maleimide and an N-hydroxysuccinimide ester group to bind to sulfhydryl groups and primary amines, respectively. Sulfo-SMCC inhibits the end-to-end annealing of stabilized Microtubules (MTs) . MTs are treated with 250 μM Sulfo-SMCC, and imaged after incubation for 0 h, 6 h, and 24 h. MTs treated with Sulfo-SMCC shows a constant mean length, independent of the incubation time.
CAS Number
92921-24-9
Purity
>98% (HPLC)
Solubility
In Vitro: DMSO : 125 mg/mL (286.45 mM)
Smiles
[Na+].[O-]S (=O) (=O) C1CC (=O) N (OC (=O) C2CCC (CN3C (=O) C=CC3=O) CC2) C1=O
Molecular Formula
C16H17N2NaO9S
Molecular Weight
436.37
Storage Conditions
Storage temperature: -20°C. Stability: ≥ 2 years
Notes
For research use only.

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