Sulfo-SMCC (sodium)

• UNSPSC Description:

  Sulfo-SMCC sodium is a commonly used hetero-bifunctional, noncleavable ADC crosslinker bearing N-hydroxysuccinimide (NHS) ester and maleimide groups to react with primary amines and sulfhydryl groups, respectively.

• Target Antigen:

  ADC Linker

• Type:

  Biochemical Assay Reagents

• Related Pathways:

  Antibody-drug Conjugate/ADC Related

• Field of Research:

  Cancer

• Assay Protocol:

  https://www.medchemexpress.com/Sulfo-SMCC_sodium.html

• Purity:

  99.70

• Solubility:

  DMSO : 125 mg/mL (ultrasonic)|H2O : 5 mg/mL (ultrasonic;warming;heat to 60°C)

• Smiles:

  O=C(C1CCC(CN2C(C=CC2=O)=O)CC1)ON3C(C(S(=O)(O[Na])=O)CC3=O)=O

• Molecular Weight:

  436.37

• References & Citations:

  [1]Prabhune M, et al. Sulfo-SMCC Prevents Annealing of Taxol-Stabilized Microtubules In Vitro. PLoS One. 2016 Aug 25;11(8):e0161623.

• Shipping Conditions:

  Room Temperature

• Storage Conditions:

  4°C (Powder, sealed storage, away from moisture and light)

• Clinical Information:

  No Development Reported

• CAS Number:

  92921-24-9