Products for Research Use Only

BML-278

CAT: 0013-GTR19213776-02Size: 25 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19213776-02Size:25 mg
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Description
BML-278 is a SIRT1 activator (EC150 ~1 μM) that modulates histone and tubulin acetylation, impacting epigenetic regulation and cell morphology. It is used in research on cellular senescence, cell cycle arrest, and early embryonic development, with applications in both in vitro and in vivo experimental models.
CAS Number
120533-76-8
Product Name Alternative
BML278, BML-278, BML 278, HistoneMethyltransferase, Histone Methyltransferase, SIRT1
Field of Research
Epigenetics & Chromatin, Neuroscience
Purity
>98%
Bioactivity
SIRT1 activator
Form
Powder
Solubility
Soluble in DMSO (up to 5 mg/ml) .
Smiles
CCOC (=O) C1=CN (Cc2ccccc2) C=C (C1c1ccccc1) C (=O) OCC
Molecular Formula
C24H25NO4
Molecular Weight
391.47
Storage Conditions
RT
Notes
For research use only.
Other Product Names
N-Benzyl-3,5-dicarbethoxy-4-phenyl-1,4-dihydropyridine

Chemical Information

Diethyl 1-benzyl-4-phenyl-1,4-dihydropyridine-3,5-dicarboxylate

4-phenyl-1-(phenylmethyl)-4H-pyridine-3,5-dicarboxylic acid diethyl ester is a dihydropyridine.

CAS Number120533-76-8
PubChem CID10620479
IUPAC Namediethyl 1-benzyl-4-phenyl-4H-pyridine-3,5-dicarboxylate
Molecular FormulaC24H25NO4
Molecular Weight391.5
XLogP4.2
Topological Polar Surface Area55.8
Hydrogen Bond Donor Count0
Hydrogen Bond Acceptor Count5
Rotatable Bond Count9
Heavy Atom Count29
Formal Charge0
Complexity591
SMILES
CCOC(=O)C1=CN(C=C(C1C2=CC=CC=C2)C(=O)OCC)CC3=CC=CC=C3
InChI
InChI=1S/C24H25NO4/c1-3-28-23(26)20-16-25(15-18-11-7-5-8-12-18)17-21(24(27)29-4-2)22(20)19-13-9-6-10-14-19/h5-14,16-17,22H,3-4,15H2,1-2H3
InChIKey
JOHFECBOWRGWJZ-UHFFFAOYSA-N
Chemical Structure
2D Structure
2D structure of Diethyl 1-benzyl-4-phenyl-1,4-dihydropyridine-3,5-dicarboxylate
CAS: 120533-76-8
CID: 10620479
Formula: C24H25NO4
MW: 391.5
Interactive 3D Structure
Loading 3D structure...
Computed Properties
PropertyValue
Molecular Weight391.5
XLogP34.2
Hydrogen Bond Donor Count0
Hydrogen Bond Acceptor Count5
Rotatable Bond Count9
Exact Mass391.17835828
Monoisotopic Mass391.17835828
Topological Polar Surface Area55.8 Ų
Heavy Atom Count29
Formal Charge0
Complexity591
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently-Bonded Unit Count1
Compound Is CanonicalizedYes