Products for Research Use Only

AFG210

CAT: 0013-GTR19210315-02Size: 50 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19210315-02Size:50 mg
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Description
AFG210 is a first-in-class, type II FLT3 inhibitor designed for research use. It potently targets both wild-type and mutant FLT3, showing efficacy in cellular assays and in vivo models of acute myeloid leukemia (AML), making it a valuable tool for oncology and kinase signaling research.
CAS Number
228400-22-4
Field of Research
Cardiovascular Research, Cell Biology, Signal Transduction
Smiles
N (C (NC1=CC=C (OC=2C=CN=CC2) C=C1) =O) C3=CC (C (F) (F) F) =CC=C3
Molecular Formula
C19H14F3N3O2
Molecular Weight
373.33
Storage Conditions
-20°C
Notes
For research use only.

Chemical Information

1-(4-(Pyridin-4-yloxy)phenyl)-3-(3-(trifluoromethyl)phenyl)urea
CAS Number228400-22-4
PubChem CID15942672
IUPAC Name1-(4-pyridin-4-yloxyphenyl)-3-[3-(trifluoromethyl)phenyl]urea
Molecular FormulaC19H14F3N3O2
Molecular Weight373.3
XLogP3.8
Topological Polar Surface Area63.3
Hydrogen Bond Donor Count2
Hydrogen Bond Acceptor Count6
Rotatable Bond Count4
Heavy Atom Count27
Formal Charge0
Complexity475
SMILES
C1=CC(=CC(=C1)NC(=O)NC2=CC=C(C=C2)OC3=CC=NC=C3)C(F)(F)F
InChI
InChI=1S/C19H14F3N3O2/c20-19(21,22)13-2-1-3-15(12-13)25-18(26)24-14-4-6-16(7-5-14)27-17-8-10-23-11-9-17/h1-12H,(H2,24,25,26)
InChIKey
DDDLGNOZDKDSEG-UHFFFAOYSA-N
Chemical Structure
2D Structure
2D structure of 1-(4-(Pyridin-4-yloxy)phenyl)-3-(3-(trifluoromethyl)phenyl)urea
CAS: 228400-22-4
CID: 15942672
Formula: C19H14F3N3O2
MW: 373.3
Interactive 3D Structure
Loading 3D structure...
Computed Properties
PropertyValue
Molecular Weight373.3
XLogP33.8
Hydrogen Bond Donor Count2
Hydrogen Bond Acceptor Count6
Rotatable Bond Count4
Exact Mass373.10381118
Monoisotopic Mass373.10381118
Topological Polar Surface Area63.3 Ų
Heavy Atom Count27
Formal Charge0
Complexity475
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently-Bonded Unit Count1
Compound Is CanonicalizedYes

Alternative Products

CatalogName
MBS5812247AFG210