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(2Z,3Z) -U0126

CAT: 0013-GTR19210184-01Size: 25 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19210184-01Size:25 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
U0126 is a potent and selective noncompetitive inhibitor of MEK1 and MEK2 (IC50: 72 nM and 58 nM, respectively), blocking the MAPK/ERK pathway. It suppresses AP-1 activity and has been used in vitro to inhibit the anchorage-independent growth of ras-transformed cells and in vivo to study cancer and neurological disease models.
CAS Number
218601-62-8
Field of Research
Signal Transduction
Smiles
C (/C (=C (/SC1=C (N) C=CC=C1) \N) /C#N) (=C (\SC2=C (N) C=CC=C2) /N) \C#N
Molecular Formula
C18H16N6S2
Molecular Weight
380.49
Storage Conditions
-20°C
Notes
For research use only.

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