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RPR-200765A Mesylayte

CAT: 0013-GTR19210180-01Size: 25 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19210180-01Size:25 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
RPR-200765A is a potent, selective p38 MAPK inhibitor (IC50=50 nM) that suppresses TNFα release in vitro (EC50=110 nM in human monocytes) and in vivo (ED50=6 mg/kg in mice) . It demonstrates oral efficacy in rat arthritis models, suggesting potential disease-modifying activity for rheumatoid arthritis research.
CAS Number
218162-38-0
Smiles
CS (O) (=O) =O.C[C@@]1 (CO[C@@H] (OC1) c1nc (c ([nH]1) -c1ccncc1) -c1ccc (F) cc1) C (=O) N1CCOCC1
Molecular Formula
C24H25FN4O4
Molecular Weight
452.48
Storage Conditions
-20°C
Notes
For research use only.

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