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Afeletecan HCl

CAT: 0013-GTR19210148-01Size: 25 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19210148-01Size:25 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Afeletecan (BAY 56-3722) is a water-soluble camptothecin conjugate that acts as a topoisomerase I inhibitor, stabilizing the enzyme-DNA complex to induce replication-dependent DNA damage and apoptosis. Its carbohydrate moiety enhances lactone stability in circulation, supporting its investigation in preclinical cancer research for both in vitro and in vivo antitumor efficacy.
CAS Number
215604-74-3
Smiles
Cl.CC[C@@]1 (OC (=O) [C@@H] (NC (=O) [C@H] (Cc2cnc[nH]2) NC (=S) Nc2ccc (O[C@H]3O[C@@H] (C) [C@@H] (O) [C@@H] (OC) [C@@H]3O) cc2) C (C) C) C (=O) OCc2c1cc1-c3nc4ccccc4cc3Cn1c2=O
Molecular Formula
C45H50ClN7O11S
Molecular Weight
932.44
Storage Conditions
-20°C
Notes
For research use only.

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