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NG25 trihydrochloride

CAT: 0013-GTR19210110-01Size: 25 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19210110-01Size:25 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
NG25 trihydrochloride is a multi-kinase inhibitor targeting MAP4K2, TAK1, Src, and Abl families. It blocks pro-inflammatory NF-κB and type I interferon signaling in vitro and demonstrates potent anti-tumor activity by reducing viability in KRAS-mutant colorectal cancer cells and suppressing tumor growth in mouse models.
CAS Number
2108554-00-1
Field of Research
Signal Transduction
Smiles
Cl.Cl.Cl.CCN1CCN (Cc2ccc (NC (=O) c3ccc (C) c (Oc4ccnc5[nH]ccc45) c3) cc2C (F) (F) F) CC1
Molecular Formula
C29H33Cl3F3N5O2
Molecular Weight
646.96
Storage Conditions
-20°C
Notes
For research use only.

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