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Lifirafenib HCl

CAT: 0013-GTR19210018-01Size: 25 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19210018-01Size:25 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Lifirafenib (BGB-283) is a novel RAF kinase and EGFR inhibitor that selectively targets cells with B-RAFV600E and EGFR alterations. It demonstrates potent antitumor activity in vitro by inhibiting ERK phosphorylation and proliferation, and in vivo by causing tumor regression in colorectal cancer xenograft models.
CAS Number
2025320-97-0
Field of Research
Metabolism Research
Smiles
Cl.[H][C@]12Oc3ccc (OC4=C5CCC (=O) N=C5NC=C4) cc3[C@@]1 ([H]) [C@@H]2c1nc2ccc (cc2[nH]1) C (F) (F) F
Molecular Formula
C26H19ClF3N3O3
Molecular Weight
513.9012
Storage Conditions
-20°C
Notes
For research use only.

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