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PH11

CAT: 0013-GTR19209630-01Size: 25 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19209630-01Size:25 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
PH11 is a novel small molecule inhibitor of Focal Adhesion Kinase (FAK) . It overcomes TRAIL resistance in cancer cells, such as PANC-1 pancreatic carcinoma, by suppressing FAK and the PI3K/AKT pathways to downregulate c-FLIP and restore apoptosis. This mechanism supports its investigation in both in vitro and in vivo oncology research models.
CAS Number
1627843-95-1
Field of Research
Cardiovascular Research, Signal Transduction
Smiles
N (C=1N2C (N=C (NC3=C (C (OC) =O) C=CC=C3) N1) =NC=C2) C4=CC (OC) =C (OC) C (OC) =C4
Molecular Formula
C22H22N6O5
Molecular Weight
450.45
Storage Conditions
-20°C
Notes
For research use only.

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