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G-749 hydrochloride

CAT: 0013-GTR19209478-01Size: 25 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19209478-01Size:25 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
G-749 hydrochloride is a potent and selective FLT3 inhibitor effective against wild-type and mutant forms, including ITD and resistance-conferring variants like D835Y and F691L. It demonstrates robust activity in cellular assays and has shown efficacy in preclinical models of FLT3-driven acute myeloid leukemia (AML), supporting its use in both in vitro and in vivo research.
CAS Number
1457983-33-3
Field of Research
Signal Transduction
Smiles
Cl.CN1CCC (CC1) Nc1nc (Nc2ccc (Oc3ccccc3) cc2) c2c (n1) c (Br) c[nH]c2=O
Molecular Formula
C25H26BrClN6O2
Molecular Weight
557.88
Storage Conditions
-20°C
Notes
For research use only.

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