Products for Research Use Only
RegisterLogin

PF05020182

CAT: 0013-GTR19208949-03Size: 100 mgDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0013-GTR19208949-03Size:100 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Description
PF-05020182 is a potent and selective opener of Kv7.2/7.4 potassium channels. Its in vitro activity translates to robust anticonvulsant effects in the MES model in vivo, supporting its research use for investigating novel therapies for refractory epilepsy and neuronal hyperexcitability.
CAS Number
1354712-92-7
Field of Research
Pharmacology & Drug Discovery
Smiles
N (C (CC (C) (C) C) =O) C=1C (OC) =NC (=NC1OC) N2CCC (OC) CC2
Molecular Formula
C18H30N4O4
Molecular Weight
366.46
Storage Conditions
-20°C
Notes
For research use only.

Chemical Information

N-(4,6-dimethoxy-2-(4-methoxypiperidin-1-yl)pyrimidin-5-yl)-3,3-dimethylbutanamide
CAS Number1354712-92-7
PubChem CID66653331
IUPAC NameN-[4,6-dimethoxy-2-(4-methoxypiperidin-1-yl)pyrimidin-5-yl]-3,3-dimethylbutanamide
Molecular FormulaC18H30N4O4
Molecular Weight366.5
XLogP2.5
Topological Polar Surface Area85.8
Hydrogen Bond Donor Count1
Hydrogen Bond Acceptor Count7
Rotatable Bond Count7
Heavy Atom Count26
Formal Charge0
Complexity435
SMILES
CC(C)(C)CC(=O)NC1=C(N=C(N=C1OC)N2CCC(CC2)OC)OC
InChI
InChI=1S/C18H30N4O4/c1-18(2,3)11-13(23)19-14-15(25-5)20-17(21-16(14)26-6)22-9-7-12(24-4)8-10-22/h12H,7-11H2,1-6H3,(H,19,23)
InChIKey
XHJMCIALHJMEBB-UHFFFAOYSA-N
Chemical Structure
2D Structure
2D structure of N-(4,6-dimethoxy-2-(4-methoxypiperidin-1-yl)pyrimidin-5-yl)-3,3-dimethylbutanamide
CAS: 1354712-92-7
CID: 66653331
Formula: C18H30N4O4
MW: 366.5
Interactive 3D Structure
Loading 3D structure...
View on PubChemRaw 3D data
Computed Properties
PropertyValue
Molecular Weight366.5
XLogP32.5
Hydrogen Bond Donor Count1
Hydrogen Bond Acceptor Count7
Rotatable Bond Count7
Exact Mass366.22670545
Monoisotopic Mass366.22670545
Topological Polar Surface Area85.8 Ų
Heavy Atom Count26
Formal Charge0
Complexity435
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently-Bonded Unit Count1
Compound Is CanonicalizedYes

Alternative Products

CatalogName
MBS5813438PF05020182

Popular Products