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SGK1 inhibitor

CAT: 0013-GTR19208940-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19208940-01Size:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
This small molecule selectively inhibits serum- and glucocorticoid-regulated kinase 1 (SGK1) and SGK2 over SGK3. It demonstrates functional activity by blocking GSK3β phosphorylation in vitro and, in combination with PI3Kα inhibitor BYL719, reduces viability of resistant cancer cells and suppresses tumor growth in xenograft models.
CAS Number
1426214-51-8
Field of Research
Metabolism Research, Pharmacology & Drug Discovery; Cell Biology
Smiles
N (S (=O) (=O) C1=C (Cl) C (Cl) =CC=C1) C2=CC=C (C=3N=C4C (=NC3) C (N) =NN4) C=C2
Molecular Formula
C17H12Cl2N6O2S
Molecular Weight
435.29
Storage Conditions
-20°C
Notes
For research use only.

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