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JNJ-pan-AR

CAT: 0013-GTR19208438-01Size: 25 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19208438-01Size:25 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
JNJ-pan-AR is a methylated derivative of the potent oral androgen receptor (AR) antagonist JNJ-63576253 (TRC253) . This novel pan-AR antagonist effectively inhibits both wild-type and mutant AR variants, such as F877L, blocking nuclear translocation and activation. It is a valuable research tool for studying prostate cancer resistance mechanisms in both cellular and animal models.
CAS Number
1332390-06-3
Smiles
O=C1C2 (N (C (=S) N1C=3C=C (C (F) (F) F) C (C#N) =NC3) C4=CC=C (OC5CCN (C) CC5) C=C4) CCC2
Molecular Formula
C25H24F3N5O2S
Molecular Weight
515.55
Storage Conditions
-20°C
Notes
For research use only.

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