Products for Research Use Only

WF 2421

CAT: 0013-GTR19208329-02Size: 50 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19208329-02Size:50 mg
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Description
WF 2421 is a small molecule aldose reductase inhibitor isolated from the fungus Humicola grisea. It is used in research to study diabetic complications, demonstrating inhibitory activity in both in vitro enzymatic assays and in vivo models of hyperglycemia.
CAS Number
128429-19-6
Smiles
OC=1C (=CC (C (C (NC=O) C (O) =O) O) =CC1) C2=CC (C (CNC=O) O) =CC=C2O
Molecular Formula
C19H20N2O8
Molecular Weight
404.37
Storage Conditions
-20°C
Notes
For research use only.

Chemical Information

WF 2421

WF-2421 is a tyrosine derivative.

CAS Number128429-19-6
PubChem CID195567
IUPAC Name2-formamido-3-[3-[5-(2-formamido-1-hydroxyethyl)-2-hydroxyphenyl]-4-hydroxyphenyl]-3-hydroxypropanoic acid
Molecular FormulaC19H20N2O8
Molecular Weight404.4
XLogP-0.6
Topological Polar Surface Area176
Hydrogen Bond Donor Count7
Hydrogen Bond Acceptor Count8
Rotatable Bond Count8
Heavy Atom Count29
Formal Charge0
Complexity562
SMILES
C1=CC(=C(C=C1C(CNC=O)O)C2=C(C=CC(=C2)C(C(C(=O)O)NC=O)O)O)O
InChI
InChI=1S/C19H20N2O8/c22-8-20-7-16(26)10-1-3-14(24)12(5-10)13-6-11(2-4-15(13)25)18(27)17(19(28)29)21-9-23/h1-6,8-9,16-18,24-27H,7H2,(H,20,22)(H,21,23)(H,28,29)
InChIKey
WQVWUCSBLUJLNT-UHFFFAOYSA-N
Chemical Structure
2D Structure
2D structure of WF 2421
CAS: 128429-19-6
CID: 195567
Formula: C19H20N2O8
MW: 404.4
Interactive 3D Structure
Loading 3D structure...
Computed Properties
PropertyValue
Molecular Weight404.4
XLogP3-0.6
Hydrogen Bond Donor Count7
Hydrogen Bond Acceptor Count8
Rotatable Bond Count8
Exact Mass404.12196560
Monoisotopic Mass404.12196560
Topological Polar Surface Area176 Ų
Heavy Atom Count29
Formal Charge0
Complexity562
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count3
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently-Bonded Unit Count1
Compound Is CanonicalizedYes