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SAR156497

CAT: 0013-GTR19208272-01Size: 25 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19208272-01Size:25 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
SAR156497 is a highly potent and selective pan-Aurora kinase inhibitor (IC50: 0.5-3 nM) demonstrating robust in vitro antiproliferative activity and in vivo target modulation. It effectively induces polyploidy and modulates biomarkers like pHH3, making it a valuable chemical probe for cancer research, particularly in studying mitosis and kinase signaling pathways.
CAS Number
1256137-14-0
Field of Research
Cell Biology, Epigenetics & Chromatin, Metabolism Research
Smiles
O=C1C=2[C@H] (C=3C (=C (C (OCC) =O) NC3) NC2CCC1) C4=CC (OC=5NC=6C (N5) =CC=CC6) =CC=C4
Molecular Formula
C27H24N4O4
Molecular Weight
468.5
Storage Conditions
-20°C
Notes
For research use only.

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