Trifloxystrobin

Trifloxystrobin

• Product Name Alternative: CGA 279202
• CAS Number: 141517-21-7
• UNSPSC Description: Trifloxystrobin (CGA 279202) is a type of fungicide. Trifloxystrobin has toxicity, antiparasitic activity and induce apoptosis, oxidative stress and DNA damage. Trifloxystrobin can be used for the reaesrch of fungal diseases[1][2][3][4][5].
• Target Antigen: Apoptosis; Caspase; Fungal; PARP
• Type: Reference compound
• Related Pathways: Anti-infection;Apoptosis;Cell Cycle/DNA Damage;Epigenetics
• Field of Research: Infection; Neurological Disease
• Assay Protocol: https://www.medchemexpress.com/Trifloxystrobin.html
• Purity: 99.68
• Solubility: DMSO : 100 mg/mL (ultrasonic)
• Smiles: C/C(C1=CC(C(F)(F)F)=CC=C1)=N\OCC2=C(C=CC=C2)/C(C(OC)=O)=N\OC
• Molecular Weight: 408.37
• References & Citations: [1]Jang Y, et al. Trifloxystrobin induces tumor necrosis factor-related apoptosis-inducing ligand (TRAIL)-mediated apoptosis in HaCaT, human keratinocyte cells [J]. Drug and Chemical Toxicology, 2017, 40(1): 67-73.|[2]Nguyen K, et al. Neurotoxicity assessment of QoI strobilurin fungicides azoxystrobin and trifloxystrobin in human SH-SY5Y neuroblastoma cells: Insights from lipidomics and mitochondrial bioenergetics[J]. Neurotoxicology, 2022, 91: 290-304.|[3]Li H, et al. Developmental toxicity, oxidative stress and immunotoxicity induced by three strobilurins (pyraclostrobin, trifloxystrobin and picoxystrobin) in zebrafish embryos [J]. Chemosphere, 2018, 207: 781-790.|[4]Wu R, et al. Oxidative stress and DNA damage induced by trifloxystrobin on earthworms (Eisenia fetida) in two soils [J]. Science of The Total Environment, 2021, 797: 149004.|[5]Villares M, et al. Trifloxystrobin blocks the growth of Theileria parasites and is a promising drug to treat Buparvaquone resistance [J]. Communications Biology, 2022, 5(1): 1253.
• Shipping Conditions: Room Temperature
• Storage Conditions: -20°C, 3 years; 4°C, 2 years (Powder)
• Clinical Information: No Development Reported