Products for Research Use Only
RegisterLogin

NPB

CAT: 0013-GTR19206851-01Size: 1 mgDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0013-GTR19206851-01Size:1 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Description
NPB (Alpha-NPB) is a potent small molecule inhibitor that blocks the phosphorylation of BAD at Ser99 with an IC50 of 0.41 μM. This compound is a valuable research tool for studying apoptosis regulation and BAD-related signaling pathways in both cellular and biochemical assays.
CAS Number
2247491-97-8
Product Name Alternative
Alpha-NPB, BAD, a-NPB, NPB, α-NPB
Field of Research
Cell Biology, Neuroscience
Purity
99.93% (May vary between batches)
Solubility
DMSO:45 mg/mL (85.8 mM)
Smiles
Oc1ccccc1C (N1CCN (CC1) c1cccc (Cl) c1Cl) c1cccc (c1) C (=O) NC1CCCC1
Molecular Formula
C29H31Cl2N3O2
Molecular Weight
524.48
Storage Conditions
-20°C
Notes
For research use only.

Chemical Information

N-cyclopentyl-3-((4-(2,3-dichlorophenyl) piperazin-1-yl) (2-hydroxyphenyl) methyl) benzamide

inhibitor of human BCL-2-associated death promoter (hBAD) phorsphorylation at Ser99

CAS Number2247491-97-8
PubChem CID135363221
IUPAC NameN-cyclopentyl-3-[[4-(2,3-dichlorophenyl)piperazin-1-yl]-(2-hydroxyphenyl)methyl]benzamide
Molecular FormulaC29H31Cl2N3O2
Molecular Weight524.5
XLogP6.5
Topological Polar Surface Area55.8
Hydrogen Bond Donor Count2
Hydrogen Bond Acceptor Count4
Rotatable Bond Count6
Heavy Atom Count36
Formal Charge0
Complexity713
SMILES
C1CCC(C1)NC(=O)C2=CC=CC(=C2)C(C3=CC=CC=C3O)N4CCN(CC4)C5=C(C(=CC=C5)Cl)Cl
InChI
InChI=1S/C29H31Cl2N3O2/c30-24-12-6-13-25(27(24)31)33-15-17-34(18-16-33)28(23-11-3-4-14-26(23)35)20-7-5-8-21(19-20)29(36)32-22-9-1-2-10-22/h3-8,11-14,19,22,28,35H,1-2,9-10,15-18H2,(H,32,36)
InChIKey
IQLVMUSOSDGQHW-UHFFFAOYSA-N
Chemical Structure
2D Structure
2D structure of N-cyclopentyl-3-((4-(2,3-dichlorophenyl) piperazin-1-yl) (2-hydroxyphenyl) methyl) benzamide
CAS: 2247491-97-8
CID: 135363221
Formula: C29H31Cl2N3O2
MW: 524.5
Interactive 3D Structure
Loading 3D structure...
View on PubChemRaw 3D data
Computed Properties
PropertyValue
Molecular Weight524.5
XLogP36.5
Hydrogen Bond Donor Count2
Hydrogen Bond Acceptor Count4
Rotatable Bond Count6
Exact Mass523.1793326
Monoisotopic Mass523.1793326
Topological Polar Surface Area55.8 Ų
Heavy Atom Count36
Formal Charge0
Complexity713
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count1
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently-Bonded Unit Count1
Compound Is CanonicalizedYes

Related Products

CatalogName
GTR19232642-01NPBA

Alternative Products

CatalogName
303-150Riboclear (RNA Cleanup)
TBS10485-100Tribio InVivoMAb Anti-Mouse TIGIT & PD-L1 Bispecific Antibody
TBS10191-1mgTetrahydrocannabinol (THC) Monoclonal Antibody
TBI3024-25MGAc-Leu-Leu-Nle-CHO (ALLN), Calpain inhibitor
122-101ExgeneTM Forensic SV mini
TBS10483-100Tribio InVivoMAb Anti-Mouse PD-L1 & CD28 Bispecific Antibody
TBS10183-1mgMonoclonal Anti-Thyroid Stimulating Hormone (TSH) Antibody
TBS10340-0.5MGInVivo Mouse IgG1 Isotype Control Antibody
121-220Exfection Plasmid EF (Exdotoxin Free, Midi)
TBS10482-100Tribio InVivoMAb Anti-Mouse PD-L1 & OX40 Bispecific Antibody

Popular Products