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CL2-SN-38

CAT: 0013-GTR19206204-01Size: 100 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19206204-01Size:100 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
CL2-SN-38 is a linker-payload designed for conjugation to the anti-Trop-2 antibody hRS7 to form an antibody-drug conjugate (ADC) . Its SN-38 component is a potent topoisomerase I inhibitor, enabling the targeted delivery of cytotoxic activity. This construct is utilized in oncology research for evaluating ADC efficacy in both in vitro and in vivo models.
CAS Number
1036969-20-6
Smiles
CCc1c2Cn3c (cc4c (COC (=O) [C@@]4 (CC) OC (=O) OCc4ccc (NC (=O) [C@H] (CCCCN) NC (=O) [C@H] (Cc5ccccc5) NC (=O) COCC (=O) NCCOCCOCCOCCOCCOCCOCCOCCOCCn5cc (CNC (=O) C6CCC (CN7C (=O) C=CC7=O) CC6) nn5) cc4) c3=O) -c2nc2ccc (O) cc12
Molecular Formula
C82H106N12O23
Molecular Weight
1627.79
Storage Conditions
-20°C
Notes
For research use only.

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