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DDR Inhibitor

CAT: 0013-GTR19206078-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19206078-01Size:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
This small molecule is a potent and selective inhibitor of discoidin domain receptors (DDRs), exhibiting an IC50 of 3.3 nM for DDR2 and 53% inhibition of DDR1 at 1.5 nM. It is a valuable research tool for studying DDR signaling in fibrosis, cancer, and arthritis in both cellular and animal models.
CAS Number
1644069-80-6
Product Name Alternative
DDR2, DDR Inhibitor, DDR1, DDR, Discoidin Domain Receptor, Discoidin Domain Receptor (DDR), DiscoidinDomainReceptor, DiscoidinDomainReceptor (DDR)
Field of Research
Pharmacology & Drug Discovery, Signal Transduction
Purity
97.75% (May vary between batches)
Solubility
10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (4.79 mM) ; DMSO:50 mg/mL (119.78 mM)
Smiles
Cc1ccc (CNC (=O) Nc2cccc (F) c2) cc1NC (=O) c1cnc2ccccn12
Molecular Formula
C23H20FN5O2
Molecular Weight
417.44
Storage Conditions
-20°C
Notes
For research use only.

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