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DHODH-IN-8

CAT: 0013-GTR19206049-01Size: 500 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19206049-01Size:500 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
DHODH-IN-8 is a potent dual inhibitor of both human and Plasmodium falciparum dihydroorotate dehydrogenase (DHODH), exhibiting antimalarial activity. It demonstrates potent inhibition with IC50 values of 0.13 μM and 47.4 μM, and Kis of 0.016 μM and 5.6 μM against the respective enzymes. This compound serves as a valuable chemical probe for researching malaria pathogenesis and DHODH-targeted therapies in both in vitro and in vivo models.
CAS Number
1148126-03-7
Product Name Alternative
Plasmodium falciparum DHODH, human DHODH, DHODH, DHODH IN 8, DHODHIN8, DHODH-IN-8
Field of Research
Cell Biology, Infectious Disease & Virology, Metabolism Research, Molecular Biology
Purity
99.57% (May vary between batches)
Solubility
DMSO:55 mg/mL (175.86 mM)
Smiles
ClC1=C (C2=CC=C (NC (/C (=C (/C) \O) /C#N) =O) C=C2) C=CC=C1
Molecular Formula
C17H13ClN2O2
Molecular Weight
312.75
Storage Conditions
-20°C
Notes
For research use only.

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Alternative Products

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T11030-01DHODH-IN-8
sc-166348DHODH (E-8)
sc-166348 PEDHODH (E-8) PE
sc-166348 HRPDHODH (E-8) HRP
sc-166348 ACDHODH (E-8) AC
sc-166348 FITCDHODH (E-8) FITC
sc-166348 AF790DHODH (E-8) Alexa Fluor® 790
sc-166348 AF488DHODH (E-8) Alexa Fluor® 488
sc-166348 AF647DHODH (E-8) Alexa Fluor® 647
sc-166348 AF680DHODH (E-8) Alexa Fluor® 680

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