Products for Research Use Only

GNE684

CAT: 0013-GTR19205743-01Size: 25 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19205743-01Size:25 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
GNE684 is a potent and selective RIP1 kinase inhibitor, demonstrating species-specific binding affinity with apparent Ki values of 21 nM (human), 189 nM (mouse), and 691 nM (rat) . This small molecule is a valuable research tool for investigating necroptosis and inflammatory pathways in both cellular and animal models of disease.
CAS Number
2438637-64-8
Field of Research
Cell Biology, Signal Transduction
Smiles
C (N[C@@H]1C (=O) N (C) C=2C (CC1) =CC (OC) =NC2) (=O) C3=NN4[C@@H] (CCC4=N3) C5=CC=CC=C5
Molecular Formula
C23H24N6O3
Molecular Weight
432.48
Storage Conditions
-20°C
Notes
For research use only.

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