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GNE684

CAT: 0931-T11442-01Size: 25 mgDry Ice: NoHazardous: No
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CAT#:0931-T11442-01Size:25 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
2438637-64-8
Target
TNF, RIP kinase
Related Pathways
Apoptosis, NF-κB
Bioactivity
GNE684 is a potent inhibitor of receptor interacting protein 1 (RIP1) with average Ki app values of 21 nM for human, 189 nM for mouse, and 691 nM for rat RIP1, respectively [1].
Smiles
C(N[C@@H]1C(=O)N(C)C=2C(CC1)=CC(OC)=NC2)(=O)C3=NN4[C@@H](CCC4=N3)C5=CC=CC=C5
Molecular Formula
C23H24N6O3
Molecular Weight
432.48
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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