Products for Research Use Only

Kira8 Hydrochloride

CAT: 0013-GTR19206057Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19206057Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Kira8 Hydrochloride is a potent and selective allosteric inhibitor of IRE1α RNase activity, exhibiting an IC50 of 5.9 nM. This small molecule is a valuable research tool for investigating the unfolded protein response (UPR) in cellular models and has been utilized in preclinical studies targeting endoplasmic reticulum stress-related diseases.
CAS Number
2250019-92-0
Field of Research
Cell Biology, Neuroscience, Pharmacology & Drug Discovery
Smiles
Cl.Cc1ccc2c (NS (=O) (=O) c3ccccc3Cl) cccc2c1Oc1ncccc1-c1ccnc (N[C@H]2CCCNC2) n1
Molecular Formula
C31H30Cl2N6O3S
Molecular Weight
637.58
Storage Conditions
-20°C
Notes
For research use only.