Products for Research Use Only
RegisterLogin

LTV-1

CAT: 0013-GTR19205508-02Size: 50 mgDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0013-GTR19205508-02Size:50 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Description
LTV-1 is a potent and selective inhibitor of lymphoid tyrosine phosphatase (LYP/PTPN22) with an IC50 of 508 nM in T cells, showing promise for autoimmune disease research. It serves as a valuable chemical probe for studying T cell receptor signaling in both cellular and animal models of autoimmunity.
CAS Number
347379-29-7
Field of Research
Metabolism Research
Smiles
Cc1ccccc1N1C (=S) NC (=O) \C (=C/c2ccc (OCc3cccc (c3) C (O) =O) cc2) C1=O
Molecular Formula
C26H20N2O5S
Molecular Weight
472.51
Storage Conditions
-20°C
Notes
For research use only.

Chemical Information

3-[(4-{(E)-[1-(2-methylphenyl)-4,6-dioxo-2-thioxotetrahydropyrimidin-5(2H)-ylidene]methyl}phenoxy)methyl]benzoic acid
CAS Number347379-29-7
PubChem CID1920999
IUPAC Name3-[[4-[(E)-[1-(2-methylphenyl)-4,6-dioxo-2-sulfanylidene-1,3-diazinan-5-ylidene]methyl]phenoxy]methyl]benzoic acid
Molecular FormulaC26H20N2O5S
Molecular Weight472.5
XLogP4.7
Topological Polar Surface Area128
Hydrogen Bond Donor Count2
Hydrogen Bond Acceptor Count6
Rotatable Bond Count6
Heavy Atom Count34
Formal Charge0
Complexity835
SMILES
CC1=CC=CC=C1N2C(=O)/C(=C/C3=CC=C(C=C3)OCC4=CC(=CC=C4)C(=O)O)/C(=O)NC2=S
InChI
InChI=1S/C26H20N2O5S/c1-16-5-2-3-8-22(16)28-24(30)21(23(29)27-26(28)34)14-17-9-11-20(12-10-17)33-15-18-6-4-7-19(13-18)25(31)32/h2-14H,15H2,1H3,(H,31,32)(H,27,29,34)/b21-14+
InChIKey
DSYDHTCEVHUCPE-KGENOOAVSA-N
Chemical Structure
2D Structure
2D structure of 3-[(4-{(E)-[1-(2-methylphenyl)-4,6-dioxo-2-thioxotetrahydropyrimidin-5(2H)-ylidene]methyl}phenoxy)methyl]benzoic acid
CAS: 347379-29-7
CID: 1920999
Formula: C26H20N2O5S
MW: 472.5
Interactive 3D Structure
Loading 3D structure...
View on PubChemRaw 3D data
Computed Properties
PropertyValue
Molecular Weight472.5
XLogP34.7
Hydrogen Bond Donor Count2
Hydrogen Bond Acceptor Count6
Rotatable Bond Count6
Exact Mass472.10929292
Monoisotopic Mass472.10929292
Topological Polar Surface Area128 Ų
Heavy Atom Count34
Formal Charge0
Complexity835
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count1
Undefined Bond Stereocenter Count0
Covalently-Bonded Unit Count1
Compound Is CanonicalizedYes

Related Products

CatalogName
GTR19169514-011,1,1,1-Kestohexaose
GTR19217879-01AMPK-α1β1γ1 activator 1
GTR191890321,1,1-Tribromoacetone
GTR18022883Ltv1 Antibody
GTR17902394-01LTV1 Antibody
GTR18017483Ltv1 Antibody
GTR18009654LTV1 Antibody
GTR17969180LTV1 Antibody
GTR191901241-Bromo-1,1-dichloroacetone
GTR19218855-01TWIK-1/TREK-1-IN-1

Alternative Products

CatalogName
BA8099-5.1LTV-1
A20901-100LTV-1 100mg
A20901-25LTV-1 25mg
A20901-50LTV-1 50mg
A20901-10LTV-1 10mg
A20901-5LTV-1 5mg
217529LYP Inhibitor II, LTV-1 (Lymphoid Tyrosine Phosphatase Inhibitor II, LTV-1, (E) -3- ((4- ((4,6-Dioxo-2-thioxo-1-o-tolyltetrahydropyrimidin-5 (6H) -ylidene) methyl) phenoxy) methyl) benzoic Acid)
OF59775-011,1,1,1,1-Kestoheptaose
N2864-5.11,1,1,1-Kestohexaose
1120401,1,1,1-Kestohexose

Popular Products