Products for Research Use Only
RegisterLogin

MBM-17

CAT: 0013-GTR19205458-02Size: 50 mgDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0013-GTR19205458-02Size:50 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Description
MBM-17 is a highly potent and selective Nek2 kinase inhibitor (IC50 = 3 nM) . It suppresses cancer cell proliferation by triggering cell cycle arrest and apoptosis, making it a valuable chemical probe for oncology research in both cellular and animal models of tumorigenesis.
CAS Number
2083621-90-1
Field of Research
Cell Biology, Epigenetics & Chromatin, Signal Transduction
Smiles
O (CC1=CC=CC=C1) C=2C=C (C=3N4C (C=C (C=C4) C5=CN (CCN (C) C) N=C5) =NC3) C=CC2C (N) =O
Molecular Formula
C28H28N6O2
Molecular Weight
480.56
Storage Conditions
-20°C
Notes
For research use only.

Chemical Information

4-[7-[1-[2-(Dimethylamino)ethyl]pyrazol-4-yl]imidazo[1,2-a]pyridin-3-yl]-2-phenylmethoxybenzamide
CAS Number2083621-90-1
PubChem CID137637358
IUPAC Name4-[7-[1-[2-(dimethylamino)ethyl]pyrazol-4-yl]imidazo[1,2-a]pyridin-3-yl]-2-phenylmethoxybenzamide
Molecular FormulaC28H28N6O2
Molecular Weight480.6
XLogP3.7
Topological Polar Surface Area90.7
Hydrogen Bond Donor Count1
Hydrogen Bond Acceptor Count5
Rotatable Bond Count9
Heavy Atom Count36
Formal Charge0
Complexity716
SMILES
CN(C)CCN1C=C(C=N1)C2=CC3=NC=C(N3C=C2)C4=CC(=C(C=C4)C(=O)N)OCC5=CC=CC=C5
InChI
InChI=1S/C28H28N6O2/c1-32(2)12-13-33-18-23(16-31-33)21-10-11-34-25(17-30-27(34)15-21)22-8-9-24(28(29)35)26(14-22)36-19-20-6-4-3-5-7-20/h3-11,14-18H,12-13,19H2,1-2H3,(H2,29,35)
InChIKey
RENORGCYKWQFMO-UHFFFAOYSA-N
Chemical Structure
2D Structure
2D structure of 4-[7-[1-[2-(Dimethylamino)ethyl]pyrazol-4-yl]imidazo[1,2-a]pyridin-3-yl]-2-phenylmethoxybenzamide
CAS: 2083621-90-1
CID: 137637358
Formula: C28H28N6O2
MW: 480.6
Interactive 3D Structure
Loading 3D structure...
View on PubChemRaw 3D data
Computed Properties
PropertyValue
Molecular Weight480.6
XLogP33.7
Hydrogen Bond Donor Count1
Hydrogen Bond Acceptor Count5
Rotatable Bond Count9
Exact Mass480.22737416
Monoisotopic Mass480.22737416
Topological Polar Surface Area90.7 Ų
Heavy Atom Count36
Formal Charge0
Complexity716
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently-Bonded Unit Count1
Compound Is CanonicalizedYes

Related Products

CatalogName
GTR19176676-01MBM-55
GTR19205455-01MBM-55S
GTR19205456-01MBM-17S
GTR17969125Mbm Antibody
GTR19268624-0117β-Carboxy-17-desoxydexamethasone
GTR19090320-01Recombinant Innexin-17 (inx-17)
GTR18874521-01Monkey Interleukin 17 (IL-17)
GTR19276195-0117-Methoxy-17-oxoheptadecanoic acid
GTR19163617-0117-Beta-Estradiol-3,17-Dipropionate
GTR18874911-01Rat 17-Hydroxycorticosteroids (17-OH-CS)

Alternative Products

CatalogName
MBS387255-01MBM-17
IID62190-01MBM 17
A12499-10MBM-17 10mg
A12499-1MBM-17 1mg
A12499-100MBM-17 100mg
A12499-50MBM-17 50mg
A12499-25MBM-17 25mg
A12499-5MBM-17 5mg
BA2886-1MBM-55
IID62209-01MBM 55

Popular Products