Products for Research Use Only
RegisterLogin

PD 90780

CAT: 0013-GTR19205193-05Size: 25 mgDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0013-GTR19205193-05Size:25 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Description
PD 90780 is a small molecule, non-peptide antagonist of nerve growth factor (NGF) that specifically disrupts the interaction between NGF and its p75NTR receptor. It demonstrates inhibitory activity with IC50 values of 23.1 μM and 1.8 μM in PC12 and PC12nnr5 cell-based assays, respectively. This compound is a valuable research tool for studying NGF signaling pathways in neurobiology, pain research, and cellular differentiation models.
CAS Number
77422-99-2
Product Name Alternative
PD 90780, PD90780, PD-90780
Field of Research
Signal Transduction
Purity
98.75% (May vary between batches)
Solubility
DMSO:28.8 mg/mL (79.48 mM)
Smiles
Cn1c2cc (nn2c (=O) c2cc (NC (=O) c3ccccc3) ccc12) C (O) =O
Molecular Formula
C19H14N4O4
Molecular Weight
362.34
Storage Conditions
-20°C
Notes
For research use only.

Chemical Information

7-Benzamido-4-methyl-9-oxopyrazolo[5,1-b]quinazoline-2-carboxylic acid
CAS Number77422-99-2
PubChem CID9885305
IUPAC Name7-benzamido-4-methyl-9-oxopyrazolo[5,1-b]quinazoline-2-carboxylic acid
Molecular FormulaC19H14N4O4
Molecular Weight362.3
XLogP2.6
Topological Polar Surface Area105
Hydrogen Bond Donor Count2
Hydrogen Bond Acceptor Count6
Rotatable Bond Count3
Heavy Atom Count27
Formal Charge0
Complexity621
SMILES
CN1C2=C(C=C(C=C2)NC(=O)C3=CC=CC=C3)C(=O)N4C1=CC(=N4)C(=O)O
InChI
InChI=1S/C19H14N4O4/c1-22-15-8-7-12(20-17(24)11-5-3-2-4-6-11)9-13(15)18(25)23-16(22)10-14(21-23)19(26)27/h2-10H,1H3,(H,20,24)(H,26,27)
InChIKey
IAZAGXDMMVWYKF-UHFFFAOYSA-N
Chemical Structure
2D Structure
2D structure of 7-Benzamido-4-methyl-9-oxopyrazolo[5,1-b]quinazoline-2-carboxylic acid
CAS: 77422-99-2
CID: 9885305
Formula: C19H14N4O4
MW: 362.3
Interactive 3D Structure
Loading 3D structure...
View on PubChemRaw 3D data
Computed Properties
PropertyValue
Molecular Weight362.3
XLogP32.6
Hydrogen Bond Donor Count2
Hydrogen Bond Acceptor Count6
Rotatable Bond Count3
Exact Mass362.10150494
Monoisotopic Mass362.10150494
Topological Polar Surface Area105 Ų
Heavy Atom Count27
Formal Charge0
Complexity621
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently-Bonded Unit Count1
Compound Is CanonicalizedYes

Related Products

CatalogName
GTR18712411-01PD-1/PD-L1 Antibody
GTR19238584-01PD-1/PD-L1-IN-53
GTR19230432-01PD-1/PD-L1-IN-32
GTR19218734-01PD-1/PD-L1-IN-34
GTR19183553-01PD-1/PD-L1-IN-9
GTR19273428-01PD-1/PD-L1-IN-59
GTR19262200-01PD-1/PD-L1-IN-41
GTR19261585-01PD-1/PD-L1-IN-40
GTR19144389-01PD-1/PD-L1-IN-42
GTR19164687-01PD-1/PD-L1-IN-10

Alternative Products

CatalogName
T12384-01PD 90780
A19821-25PD 90780 25mg
A19821-5PD 90780 5mg
A19821-100PD 90780 100mg
A19821-50PD 90780 50mg
A19821-10PD 90780 10mg
A19821-1PD 90780 1mg
A19821-10mM-DPD 90780 10mM * 1mL in DMSO
TR317702Pygopus 2 (PYGO2) Human shRNA Plasmid Kit (Locus ID 90780)
TL317702VPygopus 2 (PYGO2) Human shRNA Lentiviral Particle (Locus ID 90780)

Popular Products