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PF-04634817 succinate

CAT: 0013-GTR19205162-01Size: 25 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19205162-01Size:25 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
PF-0463481 succinate is a potent, orally bioavailable dual antagonist of the chemokine receptors CCR2 and CCR5, exhibiting an IC50 of 20.8 nM at human CCR2. This small molecule is a valuable research tool for investigating the roles of CCR2/CCR5 in inflammatory and fibrotic diseases, with utility in both in vitro binding assays and in vivo preclinical models.
CAS Number
2140301-98-8
Field of Research
Immunology & Inflammation, Infectious Disease & Virology, Neuroscience, Pharmacology & Drug Discovery
Smiles
C (CC (O) =O) C (O) =O.C (=O) ([C@]1 (C (C) C) C[C@H] (N[C@@H]2[C@H] (OC) COCC2) CC1) N3[C@@H]4CN ([C@H] (C3) C4) C=5C=C (C (F) (F) F) N=CN5
Molecular Formula
C29H42F3N5O7
Molecular Weight
629.67
Storage Conditions
-20°C
Notes
For research use only.

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A18659-50PF-04634817 50mg
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