Products for Research Use Only
RegisterLogin

BAY1238097

CAT: 0013-GTR19204986-08Size: 200 mgDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0013-GTR19204986-08Size:200 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Description
BAY1238097
CAS Number
1564268-08-1
Product Name Alternative
EpigeneticReaderDomain, Epigenetic Reader Domain, BAY1238097, BAY-1238097, BAY 1238097, BET
Field of Research
Epigenetics & Chromatin
Purity
98.10% (May vary between batches)
Solubility
DMSO:100 mg/mL (221.45 mM) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:4 mg/mL (8.86 mM)
Smiles
CNC (=O) N1N=C (c2ccc (cc2) N2CCN (C) CC2) c2cc (OC) c (OC) cc2C[C@@H]1C
Molecular Formula
C25H33N5O3
Molecular Weight
451.56
Storage Conditions
-20°C
Notes
For research use only.

Chemical Information

Bay-1238097

BET Inhibitor BAY1238097 is an inhibitor of the Bromodomain (BRD) and Extra-Terminal domain (BET) family of proteins, with potential antineoplastic activity. Upon administration, the BET inhibitor BAY1238097 binds to the acetylated lysine recognition motifs on the BRD of BET proteins, thereby preventing the interaction between BET proteins and histones. This disrupts chromatin remodeling and prevents the expression of certain growth-promoting genes. This leads to an inhibition of tumor cell growth. BET proteins (BRD2, BRD3, BRD4 and BRDT) are transcriptional regulators that bind to acetylated lysines on the tails of histones H3 and H4, and regulate chromatin structure and function; they play an important role in the modulation of gene expression during development and cellular growth.

CAS Number1564268-08-1
PubChem CID118237331
IUPAC Name(4S)-7,8-dimethoxy-N,4-dimethyl-1-[4-(4-methylpiperazin-1-yl)phenyl]-4,5-dihydro-2,3-benzodiazepine-3-carboxamide
Molecular FormulaC25H33N5O3
Molecular Weight451.6
XLogP2.4
Topological Polar Surface Area69.6
Hydrogen Bond Donor Count1
Hydrogen Bond Acceptor Count6
Rotatable Bond Count4
Heavy Atom Count33
Formal Charge0
Complexity688
SMILES
C[C@H]1CC2=CC(=C(C=C2C(=NN1C(=O)NC)C3=CC=C(C=C3)N4CCN(CC4)C)OC)OC
InChI
InChI=1S/C25H33N5O3/c1-17-14-19-15-22(32-4)23(33-5)16-21(19)24(27-30(17)25(31)26-2)18-6-8-20(9-7-18)29-12-10-28(3)11-13-29/h6-9,15-17H,10-14H2,1-5H3,(H,26,31)/t17-/m0/s1
InChIKey
CJIPEACKIJJYED-KRWDZBQOSA-N
Chemical Structure
2D Structure
2D structure of Bay-1238097
CAS: 1564268-08-1
CID: 118237331
Formula: C25H33N5O3
MW: 451.6
Interactive 3D Structure
Loading 3D structure...
View on PubChemRaw 3D data
Computed Properties
PropertyValue
Molecular Weight451.6
XLogP32.4
Hydrogen Bond Donor Count1
Hydrogen Bond Acceptor Count6
Rotatable Bond Count4
Exact Mass451.25833993
Monoisotopic Mass451.25833993
Topological Polar Surface Area69.6 Ų
Heavy Atom Count33
Formal Charge0
Complexity688
Isotope Atom Count0
Defined Atom Stereocenter Count1
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently-Bonded Unit Count1
Compound Is CanonicalizedYes

Alternative Products

CatalogName
MBS5753788BAY1238097
A16881-10BAY1238097 10mg
A16881-1BAY1238097 1mg
PMC26985-01(R) -BAY1238097
T12660-01(Rac) -BAY1238097
MBS3846020-01(R)-BAY1238097
MBS5753787(Rac)-BAY1238097
A16881-5BAY1238097 5mg
A16881-100BAY1238097 100mg
A16881-50BAY1238097 50mg

Popular Products