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Tankyrase-IN-2

CAT: 0013-GTR19204685-01Size: 25 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19204685-01Size:25 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Tankyrase-IN-2 is a potent, selective, and orally bioavailable small molecule inhibitor, demonstrating high affinity for TNKS1 (IC50=10 nM) and TNKS2 (IC50=7 nM) with significantly weaker activity against PARP1. It is a valuable chemical probe for studying Wnt/β-catenin signaling in cancer research and has been utilized in both cellular and animal models of disease.
CAS Number
1588870-36-3
Field of Research
Epigenetics & Chromatin, Molecular Biology, Signal Transduction, Stem Cell & Developmental Biology
Smiles
CC (C) (O) c1ccc (cc1) -c1nc2c (F) cc (F) cc2c (=O) [nH]1
Molecular Formula
C17H14F2N2O2
Molecular Weight
316.3
Storage Conditions
-20°C
Notes
For research use only.

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