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AZ7550

CAT: 0013-GTR19204431-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19204431-01Size:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
AZ7550, the active metabolite of the third-generation EGFR inhibitor AZD9291 (Osimertinib), also functions as an IGF1R inhibitor with an IC50 of 1.6 μM. This compound is a valuable research tool for studying IGF1R signaling in cancer models, applicable in both in vitro biochemical assays and in vivo research exploring resistance mechanisms.
CAS Number
1421373-99-0
Product Name Alternative
ALK, ACK1, AZ7550, AZ-7550, BLK, BTK, AZ 7550, Drug Metabolite, DrugMetabolite, BRK, HER1, Ins R, INSR, IGF1R, IGF-1R, EGFR, Epidermal growth factor receptor, FAK, ErbB4, ErbB-1, FES, FLT4, FLT3, Inhibitor, IRR, inhibit, MNK2, MLK1, PYK2, Tyrosine Kinases, TyrosineKinases, Txk, TEC
Field of Research
Cardiovascular Research, Metabolism Research, Signal Transduction
Purity
97.07% (May vary between batches)
Solubility
DMSO:2.56 mg/mL (5.27 mM)
Smiles
CN1C=C (C=2C1=CC=CC2) C3=NC (NC4=C (OC) C=C (N (CCNC) C) C (NC (C=C) =O) =C4) =NC=C3
Molecular Formula
C27H31N7O2
Molecular Weight
485.58
Storage Conditions
-20°C
Notes
For research use only.

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