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AMD 3465

CAT: 0013-GTR19204053-03Size: 100 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19204053-03Size:100 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
AMD 3465 is a potent and selective CXCR4 antagonist, inhibiting X4-tropic HIV-1 replication with low nanomolar IC50 values while being inactive against R5 viruses. It blocks CXCR4 ligand and antibody binding and is a valuable research tool for studying CXCR4 function in cancer metastasis, stem cell mobilization, and HIV entry in vitro.
CAS Number
185991-24-6
Field of Research
Cell Biology, Immunology & Inflammation, Infectious Disease & Virology, Pharmacology & Drug Discovery, Protein Biochemistry
Smiles
N=1C=CC=CC1CNCC2=CC=C (C=C2) CN3CCNCCCNCCNCCC3
Molecular Formula
C24H38N6
Molecular Weight
410.60
Storage Conditions
-20°C
Notes
For research use only.

Chemical Information

Amd-8664
CAS Number185991-24-6
PubChem CID483559
IUPAC NameN-(pyridin-2-ylmethyl)-1-[4-(1,4,8,11-tetrazacyclotetradec-1-ylmethyl)phenyl]methanamine
Molecular FormulaC24H38N6
Molecular Weight410.6
XLogP0.8
Topological Polar Surface Area64.3
Hydrogen Bond Donor Count4
Hydrogen Bond Acceptor Count6
Rotatable Bond Count6
Heavy Atom Count30
Formal Charge0
Complexity413
SMILES
C1CNCCNCCCN(CCNC1)CC2=CC=C(C=C2)CNCC3=CC=CC=N3
InChI
InChI=1S/C24H38N6/c1-2-13-29-24(5-1)20-28-19-22-6-8-23(9-7-22)21-30-17-4-12-26-15-14-25-10-3-11-27-16-18-30/h1-2,5-9,13,25-28H,3-4,10-12,14-21H2
InChIKey
CWJJHESJXJQCJA-UHFFFAOYSA-N
Chemical Structure
2D Structure
2D structure of Amd-8664
CAS: 185991-24-6
CID: 483559
Formula: C24H38N6
MW: 410.6
Interactive 3D Structure
Loading 3D structure...
View on PubChemRaw 3D data
Computed Properties
PropertyValue
Molecular Weight410.6
XLogP30.8
Hydrogen Bond Donor Count4
Hydrogen Bond Acceptor Count6
Rotatable Bond Count6
Exact Mass410.31579524
Monoisotopic Mass410.31579524
Topological Polar Surface Area64.3 Ų
Heavy Atom Count30
Formal Charge0
Complexity413
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently-Bonded Unit Count1
Compound Is CanonicalizedYes

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