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JWG-071

CAT: 0013-GTR19203945-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19203945-01Size:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
JWG-071 is the first reported chemical probe demonstrating selectivity for ERK5 kinase. It functions as a BET-selective inhibitor with a 1 μM IC50 for BRD4, paradoxically enhancing ERK5 activity. This probe is used in vitro to study kinase signaling crosstalk and BET bromodomain biology in cancer research.
CAS Number
2250323-50-1
Product Name Alternative
ERK5, EpigeneticReaderDomain, Epigenetic Reader Domain, JWG 071, JWG071, JWG-071, BRD4
Field of Research
Epigenetics & Chromatin, Signal Transduction
Purity
98.33% (May vary between batches)
Solubility
DMSO:61.28 mg/mL (100 mM) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (3.26 mM)
Smiles
CCC (C) N1c2ccccc2C (=O) N (C) c2cnc (Nc3ccc (cc3OC) C (=O) N3CCC (CC3) N3CCN (C) CC3) nc12
Molecular Formula
C34H44N8O3
Molecular Weight
612.77
Storage Conditions
-20°C
Notes
For research use only.

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