Products for Research Use Only
RegisterLogin

BMS-688521

CAT: 0013-GTR19203908-01Size: 1 mgDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0013-GTR19203908-01Size:1 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Description
BMS-688521 is a potent, orally bioavailable small molecule antagonist of leukocyte function-associated antigen-1 (LFA-1) that blocks its interaction with ICAM-1. This inhibitor has demonstrated anti-inflammatory activity in research, showing efficacy in both cellular adhesion assays and animal models of inflammation.
CAS Number
893397-44-9
Product Name Alternative
BMS 688521, BMS688521, BMS-688521, ICAM-1, LFA-1
Field of Research
Signal Transduction
Purity
98.87% (May vary between batches)
Solubility
10% DMSO+90% Corn Oil:5 mg/mL (9.32 mM) ; DMSO:80 mg/mL (149.15 mM)
Smiles
O=C1[C@@]2 ([C@@H] (CN (C2) C3=CC=C (C (O) =O) C=N3) C4=CC=C (C#N) C=C4) N (C) C (=O) N1C5=CC (Cl) =CC (Cl) =C5
Molecular Formula
C26H19Cl2N5O4
Molecular Weight
536.37
Storage Conditions
-20°C
Notes
For research use only.

Chemical Information

6-[(5S,9R)-9-(4-cyanophenyl)-3-(3,5-dichlorophenyl)-1-methyl-2,4-dioxo-1,3,7-triazaspiro[4.4]non-7-yl]pyridine-3-carboxylic acid
CAS Number893397-44-9
PubChem CID11699447
IUPAC Name6-[(5S,9R)-9-(4-cyanophenyl)-3-(3,5-dichlorophenyl)-1-methyl-2,4-dioxo-1,3,7-triazaspiro[4.4]nonan-7-yl]pyridine-3-carboxylic acid
Molecular FormulaC26H19Cl2N5O4
Molecular Weight536.4
XLogP3.8
Topological Polar Surface Area118
Hydrogen Bond Donor Count1
Hydrogen Bond Acceptor Count7
Rotatable Bond Count4
Heavy Atom Count37
Formal Charge0
Complexity971
SMILES
CN1C(=O)N(C(=O)[C@]12CN(C[C@H]2C3=CC=C(C=C3)C#N)C4=NC=C(C=C4)C(=O)O)C5=CC(=CC(=C5)Cl)Cl
InChI
InChI=1S/C26H19Cl2N5O4/c1-31-25(37)33(20-9-18(27)8-19(28)10-20)24(36)26(31)14-32(22-7-6-17(12-30-22)23(34)35)13-21(26)16-4-2-15(11-29)3-5-16/h2-10,12,21H,13-14H2,1H3,(H,34,35)/t21-,26+/m0/s1
InChIKey
LILGMDXLRPEBNH-HFZDXXHNSA-N
Chemical Structure
2D Structure
2D structure of 6-[(5S,9R)-9-(4-cyanophenyl)-3-(3,5-dichlorophenyl)-1-methyl-2,4-dioxo-1,3,7-triazaspiro[4.4]non-7-yl]pyridine-3-carboxylic acid
CAS: 893397-44-9
CID: 11699447
Formula: C26H19Cl2N5O4
MW: 536.4
Interactive 3D Structure
Loading 3D structure...
View on PubChemRaw 3D data
Computed Properties
PropertyValue
Molecular Weight536.4
XLogP33.8
Hydrogen Bond Donor Count1
Hydrogen Bond Acceptor Count7
Rotatable Bond Count4
Exact Mass535.0814095
Monoisotopic Mass535.0814095
Topological Polar Surface Area118 Ų
Heavy Atom Count37
Formal Charge0
Complexity971
Isotope Atom Count0
Defined Atom Stereocenter Count2
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently-Bonded Unit Count1
Compound Is CanonicalizedYes

Related Products

CatalogName
GTR19203907BMS-690514
GTR19203898-01BMS-986163
GTR19236195-01BMS-986397
GTR19231993-01BMS-986365
GTR19171953-01BMS-345541
GTR19168075-01BMS-911543
GTR19167115-01BMS-2
GTR19163585-01BMS-708163
GTR19219909-01BMS-502
GTR19218041-01BMS-496

Alternative Products

CatalogName
HY-10596-01BMS-688521
4970/10BMS 688521
A17204-100BMS-688521 100mg
A17204-50BMS-688521 50mg
A17204-5BMS-688521 5mg
A17204-25BMS-688521 25mg
A17204-10BMS-688521 10mg
A17204-1BMS-688521 1mg
A17204-10mM-DBMS-688521 10mM * 1mL in DMSO
MBS386661-01BMS-806 (BMS 378806)

Popular Products