Cdk1/2 Inhibitor III

CAT: 0013-GTR19203847-01Size: 1 mgDry Ice: NoHazardous: No

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CAT#:0013-GTR19203847-01Size:1 mg

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Description

Cdk1/2 Inhibitor III is a potent and selective small molecule targeting CDK1 and CDK2 kinases, exhibiting an IC50 of 2.1 μM against the CDK1/cyclin B complex. This inhibitor is a valuable research tool for studying cell cycle progression, proliferation, and apoptosis in various in vitro cellular models.

CAS Number

443798-55-8

Product Name Alternative

CDK2, Cdk1/cyclin B, CDK1/CyclinB, Cdk1/2 Inhibitor III, Cdk-1/2 Inhibitor III

Field of Research

Cell Biology, Pharmacology & Drug Discovery; Cell Biology

Purity

99.07% (May vary between batches)

Solubility

DMSO:45 mg/mL (105.77 mM)

Smiles

C (NC1=C (F) C=CC=C1F) (=S) N2C (NC3=CC=C (S (N) (=O) =O) C=C3) =NC (N) =N2

Molecular Formula

C15H13F2N7O2S2

Molecular Weight

425.44

Storage Conditions

-20°C

Notes

For research use only.

Chemical Information

Cdk1/2 Inhibitor III

CAS Number	443798-55-8
PubChem CID	5330812
IUPAC Name	5-amino-N-(2,6-difluorophenyl)-3-(4-sulfamoylanilino)-1,2,4-triazole-1-carbothioamide
Molecular Formula	C15H13F2N7O2S2
Molecular Weight	425.4
XLogP	2.2
Topological Polar Surface Area	181
Hydrogen Bond Donor Count	4
Hydrogen Bond Acceptor Count	10
Rotatable Bond Count	4
Heavy Atom Count	28
Formal Charge	0
Complexity	647

SMILES

C1=CC(=C(C(=C1)F)NC(=S)N2C(=NC(=N2)NC3=CC=C(C=C3)S(=O)(=O)N)N)F

InChI

InChI=1S/C15H13F2N7O2S2/c16-10-2-1-3-11(17)12(10)21-15(27)24-13(18)22-14(23-24)20-8-4-6-9(7-5-8)28(19,25)26/h1-7H,(H,21,27)(H2,19,25,26)(H3,18,20,22,23)

InChIKey

ARIOBGGRZJITQX-UHFFFAOYSA-N

Chemical Structure

2D Structure

CAS: 443798-55-8

CID: 5330812

Formula: C15H13F2N7O2S2

MW: 425.4

Interactive 3D Structure

Loading 3D structure...

View on PubChem Raw 3D data

Computed Properties

Property	Value
Molecular Weight	425.4
XLogP3	2.2
Hydrogen Bond Donor Count	4
Hydrogen Bond Acceptor Count	10
Rotatable Bond Count	4
Exact Mass	425.05402135
Monoisotopic Mass	425.05402135
Topological Polar Surface Area	181 Å²
Heavy Atom Count	28
Formal Charge	0
Complexity	647
Isotope Atom Count	0
Defined Atom Stereocenter Count	0
Undefined Atom Stereocenter Count	0
Defined Bond Stereocenter Count	0
Undefined Bond Stereocenter Count	0
Covalently-Bonded Unit Count	1
Compound Is Canonicalized	Yes

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Alternative Products

Catalog	Name
ALX-270-442-M001	CDK1/2 Inhibitor III
M33311-01	Cdk1,2 Inhibitor III
sc-202529	Cdk1 Inhibitor
USA72295-01	Cdk1/2 Inhibitor II, NU6102
sc-202094	Cdk1/5 Inhibitor
TBI4126-5MG	RO-3306, Selective CDK1 inhibitor
VID71992-01	Erk1/2 inhibitor 2
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Cdk1/2 Inhibitor III

Chemical Information

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