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IN-1130

CAT: 0013-GTR19203758-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19203758-01Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
IN-1130 is a potent and selective ALK5 inhibitor, demonstrating IC50 values of 5.3 nM for ALK5-mediated Smad3 phosphorylation, 36 nM for casein phosphorylation, and 4.3 μM for p38α MAPK. This small molecule is a valuable research tool for investigating TGF-β signaling pathways in both cellular and animal models of fibrosis and cancer.
CAS Number
868612-83-3
Product Name Alternative
IN 1130, IN1130, IN-1130, ALK5
Field of Research
Cardiovascular Research, Signal Transduction, Stem Cell & Developmental Biology
Purity
98.08% (May vary between batches)
Solubility
DMSO:90 mg/mL (214.05 mM) ;10% DMSO+90% Saline:1 mg/mL (2.38 mM)
Smiles
Cc1cccc (n1) -c1nc (Cc2cccc (c2) C (N) =O) [nH]c1-c1ccc2nccnc2c1
Molecular Formula
C25H20N6O
Molecular Weight
420.47
Storage Conditions
-20°C
Notes
For research use only.

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