Products for Research Use Only
RegisterLogin

KRN4884

CAT: 0013-GTR19203704-02Size: 50 mgDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0013-GTR19203704-02Size:50 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Description
KRN 4884 is a potent and selective KATP channel opener, demonstrating concentration-dependent activation with an EC50 of 0.55 μM even in the presence of 1 mM intracellular ATP. This small molecule is a valuable research tool for investigating KATP channel function in cardiovascular and metabolic diseases, applicable in both in vitro electrophysiology and in vivo physiological studies.
CAS Number
152802-84-1
Field of Research
Pharmacology & Drug Discovery
Smiles
C (=NCCC1=C (Cl) C=CC=C1) (NC#N) C=2C=C (N) C=NC2
Molecular Formula
C15H14ClN5
Molecular Weight
299.76
Storage Conditions
-20°C
Notes
For research use only.

Chemical Information

5-amino-N'-[2-(2-chlorophenyl)ethyl]-N-cyanopyridine-3-carboximidamide
CAS Number152802-84-1
PubChem CID9817785
IUPAC Name5-amino-N'-[2-(2-chlorophenyl)ethyl]-N-cyanopyridine-3-carboximidamide
Molecular FormulaC15H14ClN5
Molecular Weight299.76
XLogP2.2
Topological Polar Surface Area87.1
Hydrogen Bond Donor Count2
Hydrogen Bond Acceptor Count4
Rotatable Bond Count5
Heavy Atom Count21
Formal Charge0
Complexity402
SMILES
C1=CC=C(C(=C1)CCN=C(C2=CC(=CN=C2)N)NC#N)Cl
InChI
InChI=1S/C15H14ClN5/c16-14-4-2-1-3-11(14)5-6-20-15(21-10-17)12-7-13(18)9-19-8-12/h1-4,7-9H,5-6,18H2,(H,20,21)
InChIKey
NDGLGOGSZCDCPI-UHFFFAOYSA-N
Chemical Structure
2D Structure
2D structure of 5-amino-N'-[2-(2-chlorophenyl)ethyl]-N-cyanopyridine-3-carboximidamide
CAS: 152802-84-1
CID: 9817785
Formula: C15H14ClN5
MW: 299.76
Interactive 3D Structure
Loading 3D structure...
View on PubChemRaw 3D data
Computed Properties
PropertyValue
Molecular Weight299.76
XLogP32.2
Hydrogen Bond Donor Count2
Hydrogen Bond Acceptor Count4
Rotatable Bond Count5
Exact Mass299.0937732
Monoisotopic Mass299.0937732
Topological Polar Surface Area87.1 Ų
Heavy Atom Count21
Formal Charge0
Complexity402
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently-Bonded Unit Count1
Compound Is CanonicalizedYes

Alternative Products

CatalogName
MBS5769250KRN4884

Popular Products